Compass Pathways emergency podcast

June 24, 2025

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Compass Pathways ($CMPS) released an interim readout from their Phase 3 trial of Psilocybin (COMP360) for treatment resistant depression (TRD).

The data was positive and highly anticipated by the psychedelic community, but the stock dropped 50% on June 23rd. Brom Rector and Sam Tabone of XEIA Venture Partners react and comment in this emergency podcast.

We discuss:

0:00 - what did the Compass Pathways data readout actually say

12:00 - putting the Compass trial results into context vs SSRIs, Lexapro, Spravato and Ketamine

19:00 - why Compass crashed

24:00 - will Comp360 get FDA approval?

26:00 - will COMP360 be commercially successful?  

30:00 - price targets for Compass Pathways $CMPS

35:00 - will Compass get acquired?

40:00 - are we bullish or bearish on Compass?

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